01
Clinical research · Current
Personalized rTMS for treatment-resistant depression
Local coordination of the multicentre DSNATURE study, spanning participant inclusion, clinical procedures, data-quality follow-up and cross-site communication.
Physician-researcher · Paris, France
Clinical neuroscience,
made translational.
I connect medical training, neuromodulation trials, MRI-based electric-field modelling and scientific communication to make brain-stimulation research more precise and clinically interpretable.
Profile
From clinical medicine to personalized neurotechnology
My path runs from medicine and neurosurgical training through preclinical neurobiology to clinical neuroscience. Today, I work on psychiatric neuromodulation studies and the computational methods used to understand treatment response.
At EPS Ville-Evrard, I coordinate local work on a multicentre rTMS study in treatment-resistant depression, contribute to clinical procedures and protocol development, and analyse tDCS data in schizophrenia.
Alongside this work, I evaluate complex life-science and neurobiology content for AI training, with an emphasis on scientific accuracy, multimodal reasoning and quality control.
Integrated perspective
Where my disciplines meet
Medicine anchors the work. Research tests it, teaching makes it understandable, and health law and ethics keep it accountable.
Law & ethics
Clinical practice
Research
Teaching
Translational practice
Selected work
Research shaped around clinical questions
A concise selection of current and completed work across neuromodulation, modelling and patient-centred research.
02
Computational neuroscience
MRI-to-FEM-to-machine-learning pipeline
A funded prototype combining anatomical MRI, finite-element modelling and machine learning to investigate individualized TMS parameters beyond motor-threshold-only dosing.
03
Clinical neuroscience
Electric-field variability in schizophrenia
Analysis of a double-blind tDCS trial relating simulated electric-field measures and anatomical variability to PANSS and AHRS outcomes.
04
Qualitative research
Patient agency during first-experience TMS
A phenomenological study of how patients with treatment-resistant depression experience motor-threshold calibration, involuntary movement and shared agency.
Capabilities
One practice, four connected lenses
Clinical research & trial governance
Protocol development and study delivery grounded in medical training, psychiatric neuroscience, health law, research ethics and clinical-trial regulation.
- Participant inclusion and clinical procedures
- Multicentre coordination and data quality
- Research ethics, health law and clinical-trial regulation
Neuromodulation
Mechanism-informed work across non-invasive brain-stimulation modalities and cortical targets.
- rTMS and tDCS
- DLPFC and cerebellar targeting
- Treatment-response interpretation
Computational methods
Workflows connecting individual anatomy, modeled dose and clinical outcomes.
- MRI segmentation and individualized meshes
- SimNIBS and finite-element modelling
- Python analysis and visualization
Scientific communication
Translation of complex evidence for scientific, clinical, educational and AI-evaluation settings.
- Systematic review and meta-analysis
- Medical and scientific writing
- Teaching and multimodal AI quality review
Industry relevance
Clinical neuroscience expertise across brain stimulation, clinical development and medical affairs
My background connects neuroscience, neuromodulation, TMS/rTMS, tDCS and clinical research with the needs of pharma, biotech, medtech and neurotechnology teams working across CNS clinical development.
Clinical science, trials & development
Clinical trials and clinical research across neuroscience and neuropsychiatry: protocol development, participant-facing procedures, clinical endpoints, investigator collaboration, multicentre coordination, study delivery and data quality.
Medical affairs & scientific exchange
Evidence synthesis, non-promotional scientific communication, investigator training, medical writing, neuroanatomy education and translation of mechanistic neuroscience for clinical and cross-functional audiences.
Neurotechnology & computational neuromodulation
Brain stimulation with TMS, rTMS and tDCS; MRI-based anatomy, SimNIBS, finite-element electric-field modelling, individualized targeting, computational neuromodulation and treatment-response interpretation.
Scientific expertise, writing & communication
Peer-reviewed publications, meta-analysis, functional neuroscience, functional neuroanatomy, medical and scientific writing, scientific expert review, biomedical AI evaluation and evidence-based communication.
This experience is relevant to Clinical Scientist, Clinical Development, Medical Affairs, Medical Science Liaison (MSL) and Medical Advisor functions; these are areas of professional relevance and transferable expertise, not titles I am claiming to have held.
Research impact
Scientific metrics
Citation activity and scholarly reach across clinical, computational and educational neuroscience.
818Total citations
759Citations since 2021
7h-index
5i10-index
20
232
219
144
73
47
44
Google Scholar · verified 5 September 2026. Citation metrics change over time.
View live Google Scholar profileSelected publications
Evidence across clinical, computational and educational neuroscience
Published work only. Submitted and under-review manuscripts are intentionally excluded.
Journal of Affective Disorders · 2025 · First author
Transcranial direct current stimulation in patients with depression: An electric field modeling meta-analysis
Anatomical Sciences Education · 2024 · First author
Prospective Comparative Study on Enhancing Geometrical Mental Representation and Anatomical Learning in Medical Students through Modeling Clay as an Assessment Tool
Neurological Sciences · 2020 · First author
Neuroinvasion, neurotropic, and neuroinflammatory events of SARS-CoV-2: understanding the neurological manifestations in COVID-19 patients
Neuroscience Applied · 2024 · Co-author
Efficacy of transcranial direct current stimulation on prosocial behaviours: a novel meta-analytical tool based on electric field modeling
Experience
A translational trajectory
Medical Investigator & Senior Research Engineer
EPS Ville-Evrard · INSERM-linked research
Coordinates clinical neuromodulation research in depression and schizophrenia, develops protocols, and connects clinical outcomes with individualized electric-field modelling.
Neurobiology Expert, AI Training
Mercor
Evaluates complex life-science tasks for factual accuracy, multimodal reasoning and scientific quality; contributes specialist prompts, datasets and evaluation guidance.
Senior Research Engineer, Neuroscience
AP-HP Henri Mondor · INSERM U955
Conducted prospective neuromodulation research from MRI segmentation and SimNIBS simulation to clinical-score correlation in depression and schizophrenia.
Clinical Research Fellow
CEA NeuroSpin · Université Paris-Saclay · INSERM
Investigated anatomical variability in brain stimulation using 3T MRI, individualized meshes, HCP atlas targets and electric-field simulations.
Research Associate
City University of New York
Contributed to preclinical neuroscience research on taurine, epilepsy, neuroprotection and electrophysiology.
Education & training
Medicine, neuroscience, clinical trials and health law
2026
Master in Health Law (LLM) · Medical Law, Bioethics & Health
Université Paris 8 · Mention Bien · 120 ECTS2023
Master 2 · Cell Signaling & Integrative Neuroscience
Université Paris-Saclay2023
DIU · Clinical-Trial Investigator Training (FIEC)
Sorbonne Université · 180 hours2023
DIU · Psychopharmacology & Brain Stimulation Therapies
Sorbonne Université · 190 hours2023
Master 2 · Education Sciences & Instructional Engineering
Université Paris Nanterre · Mention Bien · 60 ECTS2014—2021
Doctor of Medicine (MD) · Neurosurgery training
Astrakhan State Medical UniversityMedia & expert commentary
Neuroscience expert commentary for journalists and media
Available as a scientific and neuroscience expert for evidence-based interviews, background briefings and expert commentary on neuromodulation, brain stimulation, clinical neuroscience and translational neurotechnology.
Short professional bio
Yassine Yachou is a Paris-based physician-researcher working across neuroscience, clinical neuroscience, neuropsychiatry, psychiatric neuromodulation, clinical trials and MRI-based electric-field modelling. His research includes TMS/rTMS, tDCS, individualized brain-stimulation targeting, SimNIBS/FEM modelling, functional neuroanatomy and patient-centred research.
Interview languages: French, English and Arabic.
Commentary areas
- Brain stimulation: TMS, rTMS and tDCS
- Neuromodulation, clinical neuroscience and neuropsychiatry
- Electric-field modelling, SimNIBS and computational neuromodulation
- Clinical trials, clinical research and translational neuroscience
- Neuroanatomy, functional neuroscience and neurotechnology
- Scientific evidence, medical writing and scientific communication
Contact
Interested in rigorous, human-centred neurotechnology?
Open to conversations in clinical research, neuroscience, medical affairs, scientific communication and evidence-focused biomedical AI.